Vitamin & Mineral Supplements: What Are They And Who Needs Them?

Vitamin & Mineral Supplements: What Are They And Who Needs Them?

While many healthy Americans are able to meet their daily vitamin and mineral needs through food sources, some may benefit from supplementation if they have specific deficiencies.

Vitamins are chemical compounds that are essential for normal body function. Because vitamins (with the exception of Vitamin D) cannot be created by our bodies, they must be ingested from dietary sources to meet our daily needs. There are 13 essential vitamins and the USDA has determined the recommended daily amounts (RDA) required for good health.

Minerals are naturally occurring inorganic substances used by the body to build bones, make hormones, and regulate muscle contraction among other important functions. There are two kinds of minerals: macrominerals (needed by the body in larger amounts) and trace minerals (the body needs very small amounts of trace minerals). Macrominerals include calcium, phosphorus, magnesium, sodium, potassium, chloride and sulfur. Trace minerals include iron, manganese, copper, iodine, zinc, cobalt, fluoride and selenium.

It’s important to note that vitamins and supplements are not regulated in the same manner as drugs by the Food and Drug Administration (FDA). However, manufacturers of dietary supplements are responsible for determining that their products are safe and are required to comply with Good Manufacturing Practices, a set of uniform standards established to ensure quality throughout the manufacturing, packaging, labeling, and holding of dietary supplement products. Independent reviews of supplement manufacturer quality may be obtained at several organizations including the United States Pharmacopeia, ConsumerLab.com, and NSF International. A seal of approval from one of these organizations provides assurance that the product was properly manufactured, contains the ingredients listed on the label, and does not contain harmful levels of contaminants.

Please note that the level of scientific evidence demonstrating a medical benefit varies among dietary supplement products. In some cases, including sports nutrition and weight loss supplements and with certain herbal products, there is no conclusive evidence. Those products will not be discussed here.

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Vitamin & Mineral Supplements: What Are They And Who Needs Them?

Vitamin & Mineral Supplements: What Are They And Who Needs Them?

Vitamin & Mineral Supplements: What Are They And Who Needs Them?

Funding for content provided by Bayer®
Content medically reviewed by
Author & Expert Contributors
written by
Val Jones, M.D.
Author & Expert Contributors
written by
Val Jones, M.D.
Content medically reviewed by

While many healthy Americans are able to meet their daily vitamin and mineral needs through food sources, some may benefit from supplementation if they have specific deficiencies.

Vitamins are chemical compounds that are essential for normal body function. Because vitamins (with the exception of Vitamin D) cannot be created by our bodies, they must be ingested from dietary sources to meet our daily needs. There are 13 essential vitamins and the USDA has determined the recommended daily amounts (RDA) required for good health.

Minerals are naturally occurring inorganic substances used by the body to build bones, make hormones, and regulate muscle contraction among other important functions. There are two kinds of minerals: macrominerals (needed by the body in larger amounts) and trace minerals (the body needs very small amounts of trace minerals). Macrominerals include calcium, phosphorus, magnesium, sodium, potassium, chloride and sulfur. Trace minerals include iron, manganese, copper, iodine, zinc, cobalt, fluoride and selenium.

It’s important to note that vitamins and supplements are not regulated in the same manner as drugs by the Food and Drug Administration (FDA). However, manufacturers of dietary supplements are responsible for determining that their products are safe and are required to comply with Good Manufacturing Practices, a set of uniform standards established to ensure quality throughout the manufacturing, packaging, labeling, and holding of dietary supplement products. Independent reviews of supplement manufacturer quality may be obtained at several organizations including the United States Pharmacopeia, ConsumerLab.com, and NSF International. A seal of approval from one of these organizations provides assurance that the product was properly manufactured, contains the ingredients listed on the label, and does not contain harmful levels of contaminants.

Please note that the level of scientific evidence demonstrating a medical benefit varies among dietary supplement products. In some cases, including sports nutrition and weight loss supplements and with certain herbal products, there is no conclusive evidence. Those products will not be discussed here.

Overview of Key Vitamins

Vitamins are essential nutrients that people must acquire through their diets in order for their bodies to function properly. There are a total of 13 vitamins required by the human body. They are classified into two groups based on how they dissolve: four of them are fat soluble vitamins (absorbed through the intestines and stored in body fat) and nine of them are water soluble vitamins (absorbed through the stomach and intestines and removed in the urine).

Fat Soluble Vitamins

Because these vitamins are stored in fat cells and thus are not easily removed from the body , supplements containing vitamins A, D, E and K can accumulate in the body to harmful levels if too much is taken. Recommended daily amounts of vitamins for children and adults of different ages may be found here. Please click on the highlighted vitamin and mineral names for more in depth information about them.

  • Vitamin A is important for healthy vision and immune function. It can be found in animal proteins including liver, kidney, eggs and dairy products. Carotenoids (which can be converted into Vitamin A inside the body) are found in dark green, leafy vegetables, as well as yellow vegetables and carrots.
  • Vitamin D is important for maintaining healthy levels of calcium and phosphorus, which build strong bones. Vitamin D is found in fish, eggs, fortified milk and fish oils. The body can produce Vitamin D in skin cells exposed to sunlight.
  • Vitamin E is an important antioxidant and helps to repair and protect cells from damage. Vitamin E is found in eggs, fortified cereals, fruit, green leafy vegetables, meat, nuts, nut oils, poultry, vegetable oils, argan oil, olive oil, wheat germ oil and whole grains.
  • Vitamin K is important for blood clotting. Vitamin K is found in foods including green leafy vegetables, meat and dairy products.

Water Soluble Vitamins

Water soluble vitamins (also known as B and C vitamins) are removed from the body by the kidneys and urine. Since water soluble vitamins are not stored, a regular daily intake is required to meet our physical needs. There is less danger of harm from high doses of water soluble vitamins because excess B and C vitamins are readily removed from the body. However, people with kidney damage may have difficulty eliminating excess water soluble vitamins.

  • Vitamin B-1 (also known as thiamine) plays an important role in many different body functions, including nerve and muscle functioning, enzyme processes and digestion of carbohydrates. Dietary sources of thiamine include beef, brewer’s yeast, legumes (beans, lentils), milk, nuts, oats, oranges, pork, rice, seeds, wheat, whole-grain cereals and fortified flours.
  • Vitamin B-6 (also known as pyridoxine) is required for the production of certain neurotransmitters (signaling chemicals found in the brain and nervous system) as well as nerve health. Major food sources of vitamin B-6 include cereal grains, legumes, vegetables (carrots, spinach, peas, and potatoes), milk, cheese, eggs, fish, liver, meat and flour.
  • Vitamin B-9 (also known as folic acid or folate) is required for fetal brain development and brain health in general. Dietary sources of folate include fortified cereals and flour, leafy vegetables (spinach, broccoli, lettuce), okra, asparagus, fruits (bananas, melons, lemons), legumes, yeast, mushrooms, organ meat (beef liver, kidney), orange juice and tomato juice.
  • Vitamin B-12 (also known as cobalamin) is required for protein and DNA synthesis. Major food sources include fish, shellfish, meat, eggs and dairy products.
  • Vitamin C is required for the production of collagen (in skin), as well as bones, cartilage, muscle and blood vessels. Vitamin C also assists with iron absorption in the intestine.  Good food sources of Vitamin C include fruits (especially citrus) and vegetables.

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Overview of Key Minerals

Minerals are inorganic elements that come from soil and water and are absorbed by plants. Animals and humans absorb minerals from the plants they eat and use them for important body processes. While there are many different minerals that exist in trace amounts in the body, only the most important minerals will be discussed here.

  • Calcium – Calcium is the most abundant mineral in the body and is required for building bones and teeth, for blood vessel health, muscle function, nerve transmission, intracellular signaling and hormone secretion. Good dietary sources of calcium include dairy products, sardines, fortified juice, green leafy vegetables and soy products.
  • Magnesium – Magnesium helps to regulate many chemical reactions in the body including protein synthesis, energy production, muscle and nerve function, blood glucose control and blood pressure regulation. It helps to build strong bones and is important for normal heart rhythm. Major food sources of magnesium include green leafy vegetables, legumes, nuts, seeds and whole grains. In general, foods containing dietary fiber provide magnesium.
  • Iron – Iron is critical for the production of red blood cells, which carry oxygen to all the tissues of the body. Iron also helps to regulate cell growth and development. Foods richest in iron include animal sources such as red meats, fish, and poultry. Iron can also be found in plant sources such as lentils and beans.
  • Zinc – Zinc is important for immune function, protein and DNA production, wound healing, cell division, and plays a role in our senses of taste and smell. A daily intake of zinc is required to maintain minimum levels because the body has no specialized zinc storage system. Excellent food sources of zinc include oysters, red meat, poultry, beans, nuts, crab and lobster, whole grains, fortified breakfast cereals and dairy products.

A NOTE ABOUT DYE-FREE PRODUCTS: Dye-free medications and supplements are a great option for individuals who prefer or require products without dyes, such as those with allergies, sensitivities, or personal preferences. Importantly, both dye-containing and dye-free options are held to the same rigorous safety and quality standards. If you’re unsure which is right for you or your family, talk to your pharmacist or healthcare provider. They can help you choose the option that best suits your needs.

Specific Groups Who May Benefit From Supplementation

While eating a daily variety of nutrient-dense foods generally provides sufficient intake of key vitamins and minerals, the US dietary guidelines recommend supplementation (or eating foods fortified with vitamins and minerals) under the following circumstances:

  • Women who may become pregnant should get 400 micrograms per day of folate from either food or supplements or both. Adequate folate intake reduces the risk of birth defects.
  • Women who are pregnant should take a pre-natal vitamin supplement that includes iron. This reduces the risk of birth defects, vitamin deficiencies and anemia.
  • Adults age 50 or older should eat foods fortified with vitamin B-12 or take a multivitamin that contains B-12 or a separate B-12 supplement.

"Supplemental" Information

Dietary supplements may also be appropriate in the following cases:

  • Strict calorie restriction or vegetarian diet. Adults who consume fewer than 1,600 calories per day or those who follow a vegan or vegetarian diet may be at higher risk for vitamin and mineral deficiencies.
  • Digestive problems. Adults and children who suffer from intestinal disorders that cause malabsorption syndromes (such as chronic diarrhea, celiac disease, inflammatory bowel disease, food intolerances and allergies or consequences of gastric bypass surgery) may require vitamin and mineral supplementation.
  • Bleeding disorders. Those who have chronic bleeding problems (such as hemophilia, heavy menstrual bleeding, gastrointestinal bleeds or clotting disorders) may benefit from iron supplementation.
  • Osteoporosis. Older adults at risk for weaker bones may benefit from calcium and vitamin D supplementation.
  • Wounds. Those recovering from significant wounds (including burns, recent surgeries and diabetic ulcers) may benefit from Vitamin C and zinc supplementation.
  • Macular degeneration. Specific anti-oxidant vitamins in combination with zinc may help to reduce the risk of developing this age-related eye problem.
  • Alcohol abuse. Individuals who regularly drink alcohol in excess are prone to Vitamin B and folate deficiencies.
  • Specific deficiencies. Various vitamin and mineral deficiencies can occur sporadically as a result of lack of sufficient exposure to sunlight (Vitamin D), as a side effect of medications (such as diuretics), from genetic disorders and from excessive sweat loss from certain endurance sports (such as triathlon, marathon and Ironman training).

Safe Use Tips & Takeaways

Heart Health Takeaways

If you want to be sure you are meeting your daily vitamin and mineral needs, talk with your healthcare professional about whether supplementation may benefit you. Keep in mind that vitamins and minerals have extremely important effects on the body and that overdoses may be as harmful as deficiencies. Consuming a diet rich in lean protein, dairy, fruits, grains, nuts, seeds and vegetables is the best first step for insuring that you obtain your optimal daily amounts of vitamins and minerals.

Frequently Asked Questions (FAQ)

What is fluoride?
Fluoride is a natural mineral found in water, soil, and some foods. It strengthens your enamel, repairs early signs of damage, and makes teeth more resistant to acids from bacteria and sugar.
Is fluoride toothpaste still the most effective option, or are fluoride-free formulas just as good?
Fluoride is still the gold standard for cavity protection. Fluoride-free options can clean your teeth, but they don’t offer the same enamel-strengthening power.
Is fluoride safe for daily use?
Yes. When used as directed, fluoride is safe and effective. It’s been trusted and recommended by major health organizations for over 70 years.
How does fluoride actually protect teeth?
It strengthens enamel, repairs early signs of decay, and makes teeth more resistant to acids from bacteria and sugary foods.
Are there any risks to using fluoride long-term?
The main risk—especially for young kids—is swallowing too much, which can lead to mild fluorosis. Using the right amount prevents this. For parents, supervise brushing to ensure kids spit out the toothpaste and don't swallow it. 
At what age should kids start using fluoride toothpaste?
As soon as the first tooth appears!

* Under 3 years: a tiny rice-sized smear
* Ages 3–6: a pea-size amount  

Supervise brushing so they don’t swallow it.
Is fluoride still safe and recommended for kids with all the claims online?
Yes. A lot of online claims can be confusing, but decades of research show fluoride is safe and strongly recommended for cavity prevention when used properly.
How much fluoride should my child get from toothpaste?
Use age-appropriate amounts and brush twice a day. If your water isn’t fluoridated, ask your dentist about additional options.
How do I know which kids’ toothpaste claims are real and not just marketing?
Check for the ADA Seal of Acceptance and choose brands your dentist recommends.
Do fluoride-free or “natural” toothpastes protect kids from cavities?
They can help clean teeth, but they don’t provide the same cavity protection as fluoride toothpastes.
Are fluoride-free toothpastes just as effective for adults?
Not for cavity prevention. Fluoride-free toothpastes can help with cleaning and freshening breath, but they do not protect against cavities the way fluoride does. For adults, or anyone who is prone to cavities, fluoride toothpaste remains the most effective option for preventing tooth decay.
Do fluoride alternatives like nano-hydroxyapatite (nHAp) make a difference?
Yes—nHAp can help with sensitivity and early enamel repair. But it hasn’t matched fluoride’s cavity-prevention strength in studies.
How do I compare fluoride vs. fluoride-free options if I have sensitivity or enamel wear?
Fluoride is best for strengthening enamel. nHAp may help with sensitivity. Some people benefit from using both in a balanced routine.
Are whitening toothpastes safe to use with fluoride or fluoride-free products?
Most are safe but can be abrasive. Choose gentle formulas and avoid using them every single day—especially for kids.
What should I look for when choosing an OTC toothpaste?
Pick products with proven active ingredients (like fluoride), check for the ADA Seal, and avoid unnecessary additives or sweeteners.
Does fluoride affect hormones or the brain?
No credible scientific evidence shows fluoride at levels used in toothpaste or fluoridated water disrupts hormones or causes neurodevelopmental harm.
What should I do if my community stops adding fluoride to the water?
Use fluoridated toothpaste, consider fluoride rinses, and talk to a dentist about fluoride supplements for kids.
Do fluoride supplements have side effects?
They’re safe when used under dental guidance and typically recommended for children in areas without fluoridated water.
What’s the best way to make sure I’m getting enough fluoride?
Brush twice daily with fluoride toothpaste, drink fluoridated tap water if available, and ask your dentist for personalized advice if you’re cavity-prone.

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